Titans vs. Colts Odds: Tennessee Is an Underdog Week 16 Against Indianapolis

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The Tennessee Titans play their AFC South rival Indianapolis Colts twice in 2024. The first matchup in Week 6 was won by Indianapolis. The second matchup this weekend in Week 16.

Here you'll find the best odds and lines for Titans vs. Colts found at Tennessee sportsbooks.


Key Takeaways:

  • Favorite: The Titans are underdogs against the Colts in Week 16.
  • Point Spread: The Titans are +3.5 vs. the Colts.
  • Over/Under: The over/under for Titans vs. Colts is set at 42.5.
  • Moneyline: The Titans' moneyline is +160 while the Colts' is -192.

Titans vs. Colts Odds: Quick Facts

Here are the most important facts related to odds for the TEN vs. IND Week 16 matchup. You can find odds on many of the available TN betting apps.

⭐ FavoriteIndianapolis Colts
🔢 Point SpreadTitans +3.5, Colts -3.5
📊 MoneylineTitans +160, Colts -192
📈 Game TotalOver/under 42.5 points
✅ Last VerifiedMarch 28, 2025
📅 DateSunday, Dec. 22, 2024
⌚ TimeNoon CT/1 p.m. ET
📍 LocationLucas Oil Stadium (Indianapolis)

Odds via DraftKings Sportsbook.

Who Is Favored to Win?

The Indianapolis Colts are favored to beat the Titans in their Week 16 matchup. The lines suggest the Colts will win but it will be a close matchup.

Titans vs. Colts Odds: Point Spread

The point spread for Titans vs. Colts in Week 16 is Titans +3.5, Colts -3.5. This suggests the Colts will win by a small margin.

Titans vs. Colts Odds: Moneyline

The moneyline for Titans vs. Colts is set at TEN +160 and IND -192. Betting $100 on +160 would earn $160 plus your $100 back if the Titans win. Meanwhile, betting $100 on the Colts would earn you $52.08 plus your $100 back if the Colts win straight up.

Titans vs. Colts Odds: Over/Under

The game total for the Titans and Colts Week 16 game is set at over/under 42.5 points. This suggests an average scoring game between the two, as both teams have solid defenses that could keep each other around or under 20 points.


Related Titans Betting Content:


Tennessee Titans Chances to Win vs. Indianapolis Colts

The Titans have a 36.91% chance to beat the Colts. Their chances are calculated using implied probability based on odds from DraftKings. Here is how it is calculated for each team using +160 odds for the Titans and -192 odds for the Colts:

Titans chances: 100 ÷ (160 + 100) * 100 = 38.46%
Colts chances: 192 ÷ (192 + 100) * 100 = 65.75%

However, the above percentages add up to 104.21%. This is due to the vig, which is the house edge for the sportsbook which allows them to profit off the bet. To remove the vig, we simply divide each team's chance by 104.21.

Titans chances (after vig): 38.46 ÷ 104.21 = 36.91%
Colts chances (after vig): 65.75 ÷ 104.21 = 63.09%

Note that both of the final team chances above finally equal 100%. Hence, the 36.91% chance to win for the Titans.

How Tennessee Wins vs. Indianapolis

The Titans' ability to beat the Colts will partially depend on quarterback Mason Rudolph, who is taking over for the recently-benched Will Levis. Rudolph will need to be much better than Levis has been in this game, which means playing mistake-free ball and capitalizing on any turnovers that the defense gives him.


Other Titans Matchups This Season:


How Indianapolis Wins vs. Tennessee

The Colts winning against the Titans will hinge on QB Anthony Richardson, who has begun to turn things around a bit after a rough start to the season. If he can minimize mistakes, the Colts should be able to run away with this one.

Best Prop Picks for Titans vs. Colts

The widget below uses predictive analytics and projections to find potential betting edges. Don't forget to do your own research before making any wagers.

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Exclusive Promos for Betting on the Game

There are plenty of Tennessee sports betting promos available to use for the Titans vs. Colts game. These promos can also be used on props, futures and other bets.

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How to Watch Titans vs. Colts

The Titans vs. Colts Week 16 game will air on CBS in local markets at noon CT/1 p.m. ET. Out-of-market fans can catch the game on NFL Sunday Ticket, which is exclusively on YouTube TV.

Tennessee Titans quarterback Will Levis (8) scrambles and jumps over Indianapolis Colts linebacker E.J. Speed (45), linebacker Zaire Franklin (44) and cornerback Kenny Moore II (23), on Sunday, Dec. 3, 2023, during NFL week 13 at Nissan Stadium in Nashville, Tenn.

History of Titans vs. Colts

The Titans and Colts have played each other 60 times dating back to 1970 when the teams were named the Houston Oilers and Baltimore Colts, respectively. These two teams only played each other every once in a while from 1970-2001 when the Titans/Oilers were in the AFC Central and the Colts were in the AFC East. Starting in 2002, these teams moved to the AFC South and began to face each other twice a year.

Record All-Time

The Colts lead the all-time series 38-22, and have won the last three matchups against the Titans. Tennessee does hold one playoff win over the Colts, though, back in the 1999-2000 season.

Most Recent Matchup

The last game between the Titans and Colts was played on October 13, 2024. The Colts won 20-17.

Top 5 Games

DateMatchupWinner
Dec. 3, 2023IND @ TENColts 31-28
Oct. 31, 2021TEN @ INDTitans 34-31
Jan. 2, 2011TEN @ INDColts 23-20
Dec. 3, 2006IND @ TENTitans 20-17
Jan. 16, 2000*TEN @ INDTitans 19-16

* = playoff game

FAQs

Author

Wes Roesch

Wes is an editor and writer for BetTennessee.com. Based out of the Kansas City area, Wes has covered sports professionally since 2015 with a strong emphasis on sports betting and the NFL, though he's also covered pro wrestling, UFC, college sports and more.